Pulmonology

Lung Cancer

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FDA Expands Approval of Osimertinib in Lung Cancer

EGFR inhibitor now indicated for unresectable stage III disease following chemoradiotherapy

Sep 25, 2024
FDA APPROVED osimertinib (Tagrisso) over a computer rendering of lung cancer.
Cancer Diagnoses Slow to Recover From Effects of COVID Pandemic

Actual rates for 2021 lagged behind projections

Sep 25, 2024
 A photo of test tubes of blood lying on a test form with CANCER stamped in red at the bottom.
Antibody Drug-Conjugate Shows Promising Activity in Extensive-Stage SCLC

Objective response rate was 55% with 12-mg/kg ifinatamab deruxtecan

Sep 11, 2024
WCLC over a photo of San Diego Conference Center in San Diego, CA.
Added Plinabulin Boosts OS as Later-Line Treatment for EGFR Wild-Type NSCLC

However, plinabulin plus docetaxel still "not ready for prime time," expert says

Sep 10, 2024
WCLC over a photo of San Diego Conference Center in San Diego, CA.
MET Inhibitor Increases Osimertinib Activity in EGFR+ Advanced NSCLC

Absolute improvement of almost 30%, doubling of duration of response with savolitinib

Sep 10, 2024
WCLC over a photo of San Diego Conference Center in San Diego, CA.
Perioperative Nivolumab Boosts EFS Versus Neoadjuvant-Only Nivolumab in NSCLC

Two-trial analysis shows about a 40% decreased risk of disease recurrence or death

Sep 09, 2024
WCLC over a photo of San Diego Conference Center in San Diego, CA.
Ivonescimab Tops Pembrolizumab in PD-L1-Positive, Advanced NSCLC

Novel agent nearly halved risk of progression as first-line therapy in phase III trial

Sep 09, 2024
WCLC over a photo of San Diego Conference Center in San Diego, CA.
Novel Drugs Boost Immunotherapy Activity in Resectable Lung Cancer

Add-on ADC, monoclonal antibody consistently increase pCR versus PD-1 inhibitor plus chemotherapy

Sep 09, 2024
WCLC over a photo of San Diego Conference Center in San Diego, CA.
Trial Questions Role of Dual Immunotherapy in First-Line NSCLC

In Japanese trial, nivolumab-ipilimumab didn't improve OS versus pembrolizumab, had more toxicity

Aug 22, 2024
A photo composite of vials of Opdivo and Yervoy over a computer rendering of lung cancer.
Researchers Challenge USPSTF's Lung Cancer Screening Criteria

Alternate criteria based on years of smoking has higher sensitivity and specificity, study says

Aug 20, 2024
A CT scan of healthy lungs.
Targeted First-Line Combo Approved for EGFR-Mutated Lung Cancer

Lazertinib plus amivantamab improved PFS by about 7 months versus single-agent osimertinib

Aug 20, 2024
FDA APPROVED lazertinib (Lazcluze) over a computer rendering of lung cancer.
Higher Steroid Dose for ICI Toxicity Harms Cancer Survival, Analysis Suggests

More data for discussion of controversial association between steroids, immunotherapy

Aug 19, 2024
A photo of a box of prednisolone tablets.
FDA Expands Durvalumab Label to Operable Lung Cancer

PD-L1 checkpoint inhibitor approved for use in NSCLC before and after surgery

Aug 16, 2024
FDA APPROVED durvalumab (Imfinzi) over a computer rendering of a transparent body with lung cancer highlighted.
Cancer Screening Costs Over $43 Billion a Year in the U.S., Study Estimates

Colorectal cancer screening accounted for 64% of the total amount

Aug 05, 2024
 A computer rendered cutaway of a colonoscopy.
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