Gastroenterology

News, opinions and meeting coverage in gastroenterology.

H. Pylori Testing Did Not Reduce Gastric Cancer Incidence, Mortality

— Gastric cancer incidence was lower after adjusting for certain factors in post hoc analyses

A photo of a stool collection container.

Latest in Gastroenterology

No Benefit for PD-1 Inhibitors in Certain Gastroesophageal Cancers, FDA Panel Says

Despite problematic dataset, risk/benefit profile not favorable with PD-L1 expression below 1

Sep 27, 2024
Placebos Linked to Potential Harms in IBD Clinical Trials

Alternative designs needed, researchers caution

Sep 26, 2024
Timely Skin Cancer Screening After Organ Transplant Still Lacking

Only a minority of patients adhered to SUNTRAC screening recommendations

Sep 26, 2024
Novel Monoclonal Antibody Shows Promise in Ulcerative Colitis

26% of patients receiving tulisokibart achieved clinical remission vs 1% with placebo

Sep 25, 2024
Timely Skin Cancer Screening After Organ Transplant Still Lacking

Only a minority of patients adhered to SUNTRAC screening recommendations

Novel Monoclonal Antibody Shows Promise in Ulcerative Colitis

26% of patients receiving tulisokibart achieved clinical remission vs 1% with placebo

Gastroenterology Case Studies

Child Develops Voluminous Diarrhea After Amoxicillin

Discordant test results complicate diagnosis of suspected C. difficile

 A photo of a fecal sample container.
Elderly Farmer Experiences Strange Abdominal Rash and GI Symptoms

Moral of the story: don't walk barefoot in the fields

A photo of a senior woman laying in bed grimacing and holding her stomach.
Case Shows Danger of Gallstone Ileus in Patients Over 65

Clinicians found CT scan to be best diagnostic tool

 A photo of a senior woman outdoors doubled over in pain.

More in Gastroenterology

Immunotherapy May Not Benefit All Gastroesophageal Cancer Patients, FDA Staff Says

Data since approvals suggest benefits limited to subgroups with PD-L1 expression of at least 1%

Sep 24, 2024
FDA ODAC PD-(L)1 inhibitors over a computer rendering of esophageal cancer
FDA Rejects NK1R Antagonist for Gastroparesis

Drugmaker none-too-pleased with agency's request for additional studies

Sep 19, 2024
FDA CRL tradipitant (Vanda) over a computer rendering of a stomach.
GLP-1 Drugs in MASLD Tied to Lower Risk of Cirrhosis, Death

Limited benefit seen in patients with established cirrhosis, however

Sep 16, 2024
A close up photo of an injection pen.
Another Possible Treatment Option for Intermediate-Stage Liver Cancer

Adding lenvatinib, pembrolizumab to TACE significantly improved PFS, numerically improved OS

Sep 16, 2024
ESMO over a photo of Fira Barcelona Gran Via in Barcelona, Spain.
Approved Liver Disease Drug Has No Clinical Benefit, FDA Panel Says

Agency advisors put their foot down on shaky science for Ocaliva in primary biliary cholangitis

Sep 13, 2024
FDA ADCOMM obeticholic acid (Ocaliva) over a computer rendering of a liver with the biliary tree highlighted.
HHS Proposes Rule to Increase Access to Kidney, Liver Transplants in HIV Patients

Rule would streamline criteria for organ donation from donors with HIV to recipients with HIV

Sep 13, 2024
A photo of surgeons performing a kidney transplant.
FDA Warning on Hot Flash Drug

Clinicians should perform liver blood tests before and during Veozah treatment

Sep 12, 2024
FDA WARNING fezolinetant (Veozah) over a photo of Veozah tablet, bottle and packaging.
FDA Expands Approval of IL-23 Drug to Ulcerative Colitis

In trials, guselkumab more than doubled remission rates versus placebo

Sep 12, 2024
FDA approved guselkumab (Tremfya) over a computer rendering of ulcerative colitis.
FDA Reviewers Skeptical of Ocaliva for Rare Bile Duct Disease

Agency advisory panel to examine complicated efficacy data and liver safety concerns

Sep 11, 2024
FDA ADCOMM obeticholic acid (Ocaliva) over a computer rendering of a liver with the biliary tree highlighted.
Thanks to Reddit, a New Diagnosis Is Bubbling Up Across the Nation

Botox can help "no-burp syndrome" symptoms

Sep 11, 2024
A photo of a person holding a smartphone which is displaying the Reddit logo.
Comparing Fecal Immunochemical Tests; CVD Blood Test for Women

Also in TTHealthWatch: beta-blockers after MI

Sep 07, 2024
TTUHSC EL PASO HEALTHWATCH with their logo and photos of Rick Lange, MD, and Elizabeth Tracey
Upper GI Damage Tied to Subsequent Parkinson's Disease

Mucosal damage seen on upper endoscopy associated with 76% higher Parkinson's risk

Sep 06, 2024
 An xray image of the esophagus illuminated by a barium swallow.
Should Intensified Infliximab for Refractory Acute Severe UC Be Nixed?

PREDICT-UC trial found no benefit with intensified or accelerated regimens

Sep 06, 2024
A computer rendering of monoclonal antibody treatment of ulcerative colitis.
Study Backs Skipping 5-FU Bolus in Chemo Regimens for Gastrointestinal Cancers

No difference in overall survival with versus without bolus, less toxicity without

Sep 05, 2024
A close up photo of a nurse adjusting the flow rate of an intravenous infusion.
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